Our Services

Thrombophilia

What are thrombophilias

Thrombophilias are a diverse group of acquired or genetic disorders that can increase the propensity for your blood to clot.

Such disorders include:

Factor V Leiden mutation
Prothrombin 20210A mutation
MTHFR mutation
Protein C deficiency
Protein S deficiency
Antithrombin III deficiency
Antiphospholipid antibody syndrome
Lupus anticoagulant

How does thrombophilia affect pregnancy?

Thrombophilia increases the risk for abnormal blood clot formation, such as deep vein thrombosis and pulmonary embolism. Additionally, certain pregnancy complications such as repetitive miscarriages, intrauterine growth restriction, intrauterine fetal demise and preeclampsia may be more likely to occur.

How is thrombophilia managed in pregnancy?

Management of thrombophilias in pregnancy is directed to help prevent these potential complications. The perinatologists at SFPA work in conjunction with your doctor to develop a plan of treatment. This may include medications to thin your blood, serial ultrasounds to follow fetal growth, and third trimester Antepartum Testing. Despite the increased risk for pregnancy complications in patients with a thrombophilia, the majority of cases will have a good outcome.